Cereblon Binding Assay Kit |
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79899 |
BPS Bioscience |
96 rxns. |
EUR 600 |
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Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader. |
Binding Assay Laboratories manufactures the spr assay binding reagents distributed by Genprice. The Spr Assay Binding reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact binding assay. Other Spr products are available in stock. Specificity: Spr Category: Assay Group: Binding
Total Iron-Binding Capacity (TIBC) and Serum Iron Assay Kit (Colorimetric) |
|
Biovision |
each |
EUR 698.4 |
XTT CELL VIABILITY ASSAY KIT (1000 ASSAY) |
|
Biotium |
1KIT |
EUR 283.2 |
|
Description: Minimum order quantity: 1 unit of 1KIT |
MTT Cell Proliferation and Cytotoxicity Assay Kit |
|
BosterBio |
1 kit (for 500 assays) |
EUR 115.2 |
CF488A and 7-AAD Apoptosis Assay Kit |
|
Biotium |
1KIT |
EUR 339.6 |
|
Description: Minimum order quantity: 1 unit of 1KIT |
MTT Cell Proliferation and Cytotoxicity Assay Kit |
|
Abbexa |
500 tests |
EUR 284.4 |
|
|
Cell Proliferation and Cytotoxicity MTT Assay Kit |
|
GenDepot |
100 Assays |
EUR 198 |
Cell Proliferation and Cytotoxicity MTT Assay Kit |
|
GenDepot |
500 Assays |
EUR 360 |
Binding information
Cell Meterâ„¢ Live Cell Caspase 2 Binding Assay Kit *Green Fluorescence* |
|
20111-25Tests |
AAT Bioquest |
25 Tests |
EUR 334 |
|
|
|
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases. |
Cell Meterâ„¢ Live Cell Caspase 6 Binding Assay Kit *Green Fluorescence* |
|
20113-25Tests |
AAT Bioquest |
25 Tests |
EUR 334 |
|
|
|
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases. |
Cell Meterâ„¢ Live Cell Caspase 8 Binding Assay Kit *Green Fluorescence* |
|
20115-25Tests |
AAT Bioquest |
25 Tests |
EUR 334 |
|
|
|
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases. |
Cell Meterâ„¢ Live Cell Caspase 9 Binding Assay Kit *Green Fluorescence* |
|
20117-25Tests |
AAT Bioquest |
25 Tests |
EUR 334 |
|
|
|
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases. |
Cell Meterâ„¢ Live Cell Caspase 10 Binding Assay Kit *Green Fluorescence* |
|
20119-25Tests |
AAT Bioquest |
25 Tests |
EUR 334 |
|
|
|
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases. |
Cell Meterâ„¢ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence* |
|
20125-25Tests |
AAT Bioquest |
25 Tests |
EUR 334 |
|
|
|
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases. |
Cell Meter™ Live Cell Caspase 8 Binding Assay Kit *Red Fluorescence* |
|
20116 |
AAT Bioquest |
25 Tests |
EUR 372 |
Cell Meterâ„¢ Live Cell Caspase 3/7 Binding Assay Kit *Red Fluorescence* |
|
20101-25Tests |
AAT Bioquest |
25 Tests |
EUR 334 |
|
|
|
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases. |
Cell Meter™ Live Cell Caspase 1 Binding Assay Kit *Green Fluorescence* |
|
20108 |
AAT Bioquest |
25 Tests |
EUR 334 |
Cell Meter™ Live Cell Caspase 2 Binding Assay Kit *Green Fluorescence* |
|
20111 |
AAT Bioquest |
25 Tests |
EUR 334 |
Cell Meter™ Live Cell Caspase 6 Binding Assay Kit *Green Fluorescence* |
|
20113 |
AAT Bioquest |
25 Tests |
EUR 334 |
Cell Meter™ Live Cell Caspase 8 Binding Assay Kit *Green Fluorescence* |
|
20115 |
AAT Bioquest |
25 Tests |
EUR 334 |
Cell Meter™ Live Cell Caspase 9 Binding Assay Kit *Green Fluorescence* |
|
20117 |
AAT Bioquest |
25 Tests |
EUR 334 |
Cell Meter™ Live Cell Caspase 10 Binding Assay Kit *Green Fluorescence* |
|
20119 |
AAT Bioquest |
25 Tests |
EUR 334 |
Cell Meter™ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence* |
|
20125 |
AAT Bioquest |
25 Tests |
EUR 334 |
Cell Meterâ„¢ Live Cell Caspase 3/7 Binding Assay Kit *Green Fluorescence* |
|
20100-25Tests |
AAT Bioquest |
25 Tests |
EUR 334 |
|
|
|
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases. |
CoviDrop SARS-CoV-2 Spike-ACE2 Binding Activity/Inhibition Assay Kit |
|
D-1005 |
EpiGentek |
|
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