Cereblon Binding Assay Kit |
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79899 |
BPS Bioscience |
96 rxns. |
EUR 600 |
|
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader. |
Binding Assay Laboratories manufactures the spr assay binding reagents distributed by Genprice. The Spr Assay Binding reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact binding assay. Other Spr products are available in stock. Specificity: Spr Category: Assay Group: Binding
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Description: This product includes 60 ul of 1000 x PSA dye for more than 200 assays with the assay volume of 0.3 ml using 96-well plates or cuvettes. |
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Description: Antibiotic Assay Medium No.3 (Assay |
Binding information
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C47498-100ul |
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|
Description: eEF1A2 binding protein Rabbit Polyclonal Antibody |
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|
C47498-50ul |
Assay Biotech |
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|
Description: eEF1A2 binding protein Rabbit Polyclonal Antibody |
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|
Description: This product includes 150 µl of 10 x Buffer, 150 µl of 10 x ssDNA, 150 µl of 2 mg/ml E. coli single-strand DNA binding protein SSB and 100 µl of 4 x gel loading buffer. |
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|
E-BC-K071-M-48T |
Elabscience Biotech |
48T |
EUR 15 |
|
|
|
Description: Quantitative |
Total Iron Binding Capacity -TIBC- Colorimetric Assay Kit |
|
E-BC-K071-M-96T |
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96T |
EUR 220 |
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Description: Quantitative |
Total Iron Binding Capacity -TIBC- Colorimetric Assay Kit |
|
E-BC-K071-M-each |
Elabscience Biotech |
each |
Ask for price |
|
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|
Description: Quantitative |
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|
E-BC-K071-S-50Assays |
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50 Assays |
EUR 180 |
|
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Description: Quantitative |
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E-BC-K071-S-each |
Elabscience Biotech |
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Description: Quantitative |
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MyBiosource |
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MBS2563953-5x96Tests |
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