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Fluorescent Ligand Binding Assay

Cereblon Binding Assay Kit
79899 96 rxns.
EUR 600
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader.

Binding Assay Laboratories manufactures the fluorescent ligand binding assay reagents distributed by Genprice. The Fluorescent Ligand Binding Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact binding assay. Other Fluorescent products are available in stock. Specificity: Fluorescent Category: Ligand Group: Binding Assay

Retinol binding protein Assay Kit
R1：45ml×1R2：15ml×1
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UGT Activity Assay / Ligand Screening Kit (Fluorometric)
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PPAR? Ligand Screening/Characterization Assay Kit (Fluorometric)
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Creatinine Assay Kit (urine normalizing assay)
1Kit
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Creatinine Assay Kit (urine normalizing assay)
5x1Kit
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Antibiotic Assay Medium No.3 (Assay
1 unit
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Description: Antibiotic Assay Medium No.3 (Assay

Antibiotic Assay Medium No.3 (Assay
1 unit
EUR 41.3
Description: Antibiotic Assay Medium No.3 (Assay

Binding Assay information

Cell Meterâ„¢ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence*
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Cell Meterâ„¢ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence*
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Cell Meterâ„¢ Generic Fluorimetric Caspase Binding Assay Kit *Red Fluorescence Optimized for Flow Cytometry*
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Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Red Fluorescence Optimized for Flow Cytometry*
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Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.

Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Green Fluorescence Optimized for Flow Cytometry*
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Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.

Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Orange Fluorescence Optimized for Flow Cytometry*
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Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Deep Red Fluorescence Optimized for Flow Cytometry*
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Human IgA AssayLite™ Fluorescent Immunoassay Kit
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Human IgG AssayLite™ Fluorescent Immunoassay Kit
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