Fluorescent Ligand Binding Assay

Cereblon Binding Assay Kit

79899 96 rxns.
EUR 600
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader.

Binding Assay Laboratories manufactures the fluorescent ligand binding assay reagents distributed by Genprice. The Fluorescent Ligand Binding Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact binding assay. Other Fluorescent products are available in stock. Specificity: Fluorescent Category: Ligand Group: Binding Assay

PPAR? Ligand Screening/Characterization Assay Kit (Fluorometric)

each
EUR 1161.6

UGT Activity Assay / Ligand Screening Kit (Fluorometric)

each
EUR 588

Ring1 And YY1 Binding Protein (RYBP) Magnetic Luminex Assay Kit

96T
EUR 966

H2O2 and POD Assay Kit (Fluorometric)

100 tests
EUR 145

Protein stability and aggregation assay kit

200 assays
EUR 112.31
Description: This product includes 60 ul of 1000 x PSA dye for more than 200 assays with the assay volume of 0.3 ml using 96-well plates or cuvettes.

HDL and LDL/VLDL Assay Kit

100 assays
EUR 898

PCSK9[Biotinylated]-LDLR Binding Assay Kit

96 rxns.
EUR 805
Description: The PCSK9[Biotinylated]-LDLR Binding Assay Kit is designed for screening and profiling purposes. The key to this kit is the high sensitivity of detection of biotin-labeled PCSK9 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, LDLR ectodomain is coated on a 96-well plate. Next, PCSK9 is incubated with LDLR on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Binding Assay information

Cell Meterâ„¢ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence*

20125 25 Tests
EUR 341
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence*

20125-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 3/7 Binding Assay Kit *Green Fluorescence*

20100 25 Tests
EUR 341
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 3/7 Binding Assay Kit *Green Fluorescence*

20100-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Green Fluorescent Protein (GFP) Magnetic Luminex Assay Kit

LKU607378-96T 96T
EUR 1125.9

Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Blue Fluorescence Excited at 405 nm*

22828-100Tests 100 Tests
EUR 222
Description: Our Cell Meterâ„¢ assay kits are a set of tools for monitoring cell viability.

Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Green Fluorescence Excited at 405 nm*

22829-100Tests 100 Tests
EUR 222
Description: Our Cell Meterâ„¢ assay kits are a set of tools for monitoring cell viability.

Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Orange Fluorescence Excited at 405 nm*

22830-100Tests 100 Tests
EUR 222
Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.

Cell Meterâ„¢ Generic Fluorimetric Caspase Binding Assay Kit *Red Fluorescence Optimized for Flow Cytometry*

22822-100Tests 100 Tests
EUR 222
Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.

Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Red Fluorescence Optimized for Flow Cytometry*

22826-100Tests 100 Tests
EUR 222
Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.

Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Green Fluorescence Optimized for Flow Cytometry*

22824-100Tests 100 Tests
EUR 222
Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.

Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Orange Fluorescence Optimized for Flow Cytometry*

22825-100Tests 100 Tests
EUR 222
Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.

Cell Meterâ„¢ Annexin V Binding Apoptosis Assay Kit *Deep Red Fluorescence Optimized for Flow Cytometry*

22827-100Tests 100 Tests
EUR 222
Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.

Human IgA AssayLite™ Fluorescent Immunoassay Kit

FEI7001 96 Well Plate
EUR 280

Human IgG AssayLite™ Fluorescent Immunoassay Kit

FEI7200 96 Well Plate
EUR 280

Human IgM AssayLite™ Fluorescent Immunoassay Kit

FEI7301 96 Well Plate
EUR 280

Human Retinol-Binding Protein (RBP) AssayLite™ Fluorescent Immunoassay Kit

FER1005 96 Well Plate
EUR 280