Clk-N002-10 (Jena Bioscience

Individual Jena Bioscience Screen Condition, 10 ml (Classic, Basic, Membrane, Cryo, Kinase, PEG/Salt) Indicate screen and condition # when placing the order

M-CS-IND-10ML 10 ml
EUR 116
Description: Individual Jena Bioscience Screen Condition, 10 ml (Classic, Basic, Membrane, Cryo, Kinase, PEG/Salt) Indicate screen and condition # when placing the order

Human IgG antibody Laboratories manufactures the clk-n002-10 (jena bioscience reagents distributed by Genprice. The Clk-N002-10 (Jena Bioscience reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Jena Bioscience GmbH. Other Clk-N002-10 products are available in stock. Specificity: Clk-N002-10 Category: (Jena Group: Bioscience

True north Cryobox 5mLBlue

PK10
EUR 153.6

True north Cryobox 15mLNatural

PK10
EUR 212.4

True north Cryobox 15mLBlue

PK10
EUR 212.4

True north Cryobox 50mLNatural

PK10
EUR 210

True north Cryobox 50mLBlue

PK10
EUR 210

True north Cryobox1.5/2mLNatural

PK10
EUR 162

True north Cryobox1.5/2.0mLGreen

PK10
EUR 162

Bioscience information

Spike S1 (K417T, E484K, N501Y), Avi-His-Tag, Biotin-Labeled (SARS-CoV-2)

101082-2 50 µg
EUR 435
Description: Recombinant SARS-CoV-2 Spike protein S1 subunit, encompassing amino acids 16-685. This protein contains three mutations of interest K417T, E484K and N501Y (found in the RBD domain of some variants of concern). The construct contains a C-terminal Avi-Tag™ followed by a His-tag (6xHis). The protein was enzymatically biotinylated using the Avi-Tag™ and affinity purified. 

Spike S1 (K417T, E484K, N501Y), Avi-His-Tag, Biotin-Labeled (SARS-CoV-2)

101082-3 500 µg_x000D_
EUR 3800
Description: Recombinant SARS-CoV-2 Spike protein S1 subunit, encompassing amino acids 16-685. This protein contains three mutations of interest K417T, E484K and N501Y (found in the RBD domain of some variants of concern). The construct contains a C-terminal Avi-Tag™ followed by a His-tag (6xHis). The protein was enzymatically biotinylated using the Avi-Tag™ and affinity purified. 

Tau-383 (N352H) Protein

90310 20 µg
EUR 270
Description: Human Tau-383 (N352H) Protein, GenBank Accession No. P10636-6, full length, expressed in an E. coli expression system. MW = 51 kDa.

Tau-441 (N279K) Protein

90347 20 µg
EUR 270
Description: Human Tau-441 with a N279K mutation, GenBank Accession No. P10636-8, full length, expressed in an E. coli expression system. MW = 64 kDa.

PI3 Kinase [p110α (N345K)/p85α], His-Tag

40646 10 µg
EUR 465
Description: Complex of recombinant full-length human p110α (GenBank Accession No. NM_006218.2) with N345K mutation and N-terminal His-Tag, and recombinant full length, human p85α (GenBank Accession No. NM_181523), no tag. Co-expressed in Sf9 cells in a Baculovirus expression system. p110α (N345K) MW=111 kDa, p85α MW=86 kDa.

FGFR3 (N540K) His-Tag (Dephosphorylated)

100907 10 µg
EUR 375
Description: Dephosphorylated recombinant FGFR3 (Fibroblast Growth Factor Receptor 3) encompassing a.a. 397-806, with an N540K mutation and an N-terminal His-Tag. This protein was co-expressed with PTP1B for dephosphorylation. Phosphorylation level <5%.

Spike Trimer (S1+S2) (K417T, E484K, N501Y), His- Tag (SARS-CoV-2)

100988-1 100 µg
EUR 320
Description: Recombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein contains three mutations: K417T, E484K and N501Y that have been found in emerging SARS-CoV-2 Variants of Concern and may lead to higher transmissibility and infectivity. This mutant Spike Trimer will be useful for structure-function studies, testing of neutralizing antibodies, or antibody and drug screening.  The construct also contains a C-terminal His-tag. Note that the expected MW of the S1+S2 monomer is 136kDa but migrates at a higher MW in SDS-PAGE due to glycosylation. The recombinant protein is ?90% pure following affinity purification.

Spike Trimer (S1+S2) (K417T, E484K, N501Y), His- Tag (SARS-CoV-2)

100988-2 1 mg
EUR 2850
Description: Recombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein contains three mutations: K417T, E484K and N501Y that have been found in emerging SARS-CoV-2 Variants of Concern and may lead to higher transmissibility and infectivity. This mutant Spike Trimer will be useful for structure-function studies, testing of neutralizing antibodies, or antibody and drug screening.  _x000D_The construct also contains a C-terminal His-tag. Note that the expected MW of the S1+S2 monomer is 136kDa but migrates at a higher MW in SDS-PAGE due to glycosylation. The recombinant protein is ?90% pure following affinity purification.

Spike S1 (K417T, E484K, N501Y), Avi-His-Tag (SARS-CoV-2)

101081-1 100 µg
EUR 320
Description: Recombinant SARS-CoV-2 Spike protein, S1 subunit encompassing amino acids 16-685. This protein contains three mutations of interest K417T, E484K and N501Y, in addition to 682RRAR685>A. The construct also contains a C-terminal Avi-Tag™ followed by a His-tag (6xHis). The recombinant protein was affinity purified.

Spike S1 (K417T, E484K, N501Y), Avi-His-Tag (SARS-CoV-2)

101081-2 1 mg
EUR 2850
Description: Recombinant SARS-CoV-2 Spike protein, S1 subunit encompassing amino acids 16-685. This protein contains three mutations of interest K417T, E484K and N501Y, in addition to 682RRAR685>A. The construct also contains a C-terminal Avi-Tag™ followed by a His-tag (6xHis). The recombinant protein was affinity purified.

4L Bioscint

NAT1438 4L
EUR 232.8

Spike S1 RBD (K417T, E484K, N501Y), Avi-His-Tag (SARS-CoV-2)

100993-1 100 µg
EUR 335
Description: Recombinant SARS-CoV-2 Spike protein, RBD (Receptor Binding Domain) encompassing amino acids 319-541. This protein corresponds to the RBD of SARS-CoV-2 Variant P.1, originally discovered in Brazil, and contains the three mutations  K417T, E484K and N501Y. It also contains a C-terminal Avi-Tag™ and a C-terminal His-tag. The recombinant protein is ≥90% pure following affinity purification.

Spike S1 RBD (K417T, E484K, N501Y), Avi-His-Tag (SARS-CoV-2)

100993-2 1 mg
EUR 2995
Description: Recombinant SARS-CoV-2 Spike protein, RBD (Receptor Binding Domain) encompassing amino acids 319-541. This protein corresponds to the RBD of SARS-CoV-2 Variant P.1, originally discovered in Brazil, and contains the three mutations  K417T, E484K and N501Y. It also contains a C-terminal Avi-Tag™ and a C-terminal His-tag. The recombinant protein is ≥90% pure following affinity purification.

Spike S1 (K417T, E484K, N501Y) (SARS-CoV-2): ACE2 TR-FRET Assay Kit

78293 384 rxns.
EUR 930
Description: The Spike S1 (K417T, E484K, N501Y) (SARS-CoV-2): ACE2 TR-FRET Assay is designed to measure the inhibition of the binding between SARS-CoV-2 Spike S1 (K417T, E484K, N501Y) and human ACE2 in a homogeneous 384 reaction format. This TR-FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; the test inhibitor compound is incubated with biotinylated Spike S1, Eu-labeled ACE2, and dye-labeled acceptor for one hour. Then the TR-FRET signal is measured using a fluorescence reader capable of measuring Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET).

Spike (K417T, E484K, N501Y) (SARS-CoV-2) Pseudotyped Lentivirus (Luc Reporter)

78143-1 100 µl
EUR 835
Description: The Spike (K417T, E484K, N501Y) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Variant Spike (Genbank Accession #QHD43416.1 with mutations K417T, E484K, and N501Y) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (SARS-CoV-2, K417T, E484K, N501Y) pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 K417T, E484K, N501Y variant in intact cells using a Biosafety Level 2 facility._x000D_

Spike (K417T, E484K, N501Y) (SARS-CoV-2) Pseudotyped Lentivirus (Luc Reporter)

78143-2 500 µl x 2
EUR 4195
Description: The Spike (K417T, E484K, N501Y) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Variant Spike (Genbank Accession #QHD43416.1 with mutations K417T, E484K, and N501Y) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (SARS-CoV-2, K417T, E484K, N501Y) pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 K417T, E484K, N501Y variant in intact cells using a Biosafety Level 2 facility._x000D_

Spike RBD (B.1.1.7 Variant) (N501Y) (SARS-CoV-2): ACE2 Inhibitor Screening Colorimetric Assay Kit

78133 96 rxns.
EUR 995
Description: The Spike RBD (SARS-CoV-2) UK variant (N501Y):ACE2 Inhibitor Screening Colorimetric Assay Kit is designed for screening and profiling inhibitors of the interaction of ACE2 with the UK variant (N501Y) of the SARS-CoV-2 Spike RBD protein. The key to this kit is the high sensitivity of detection of ACE2-Biotin protein by Streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, Spike RBD protein UK variant is coated on a 96-well transparent plate. Next, ACE2-Biotin is incubated with Spike RBD UK variant on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce color, which can then be measured using a UV/Vis spectrophotometer microplate reader.