Biologist In Binding Assay

Cereblon Binding Assay Kit

79899 96 rxns.
EUR 600
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader.

Binding Assay Laboratories manufactures the biologist in binding assay reagents distributed by Genprice. The Biologist In Binding Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact binding assay. Other Biologist products are available in stock. Specificity: Biologist Category: In Group: Binding Assay

PCSK9[Biotinylated]-LDLR Binding Assay Kit

96 rxns.
EUR 805
Description: The PCSK9[Biotinylated]-LDLR Binding Assay Kit is designed for screening and profiling purposes. The key to this kit is the high sensitivity of detection of biotin-labeled PCSK9 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, LDLR ectodomain is coated on a 96-well plate. Next, PCSK9 is incubated with LDLR on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

SeraMir Control spike-in Small RNA and qPCR assay

100 assays
EUR 181

Total Iron-Binding Capacity (TIBC) and Serum Iron Assay Kit (Colorimetric)

each
EUR 698.4

XTT CELL VIABILITY ASSAY KIT (1000 ASSAY)

1KIT
EUR 283.2
Description: Minimum order quantity: 1 unit of 1KIT

MTT Cell Proliferation and Cytotoxicity Assay Kit

1 kit (for 500 assays)
EUR 115.2

CF488A and 7-AAD Apoptosis Assay Kit

1KIT
EUR 339.6
Description: Minimum order quantity: 1 unit of 1KIT

MTT Cell Proliferation and Cytotoxicity Assay Kit

500 tests
EUR 284.4

Binding Assay information

ExoQuant? Tumor-derived Exosome enrichment and Quantification Assay Kit (Biological Fluids/Cell Media, Luminometric)

K1209-100 each
EUR 1161.6

Cell Meterâ„¢ Live Cell Caspase 1 Binding Assay Kit *Green Fluorescence*

20108-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 2 Binding Assay Kit *Green Fluorescence*

20111-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 6 Binding Assay Kit *Green Fluorescence*

20113-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 8 Binding Assay Kit *Green Fluorescence*

20115-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 9 Binding Assay Kit *Green Fluorescence*

20117-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 10 Binding Assay Kit *Green Fluorescence*

20119-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence*

20125-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meter™ Live Cell Caspase 8 Binding Assay Kit *Red Fluorescence*

20116 25 Tests
EUR 372

Cell Meterâ„¢ Live Cell Caspase 3/7 Binding Assay Kit *Red Fluorescence*

20101-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meter™ Live Cell Caspase 1 Binding Assay Kit *Green Fluorescence*

20108 25 Tests
EUR 334

Cell Meter™ Live Cell Caspase 2 Binding Assay Kit *Green Fluorescence*

20111 25 Tests
EUR 334

Cell Meter™ Live Cell Caspase 6 Binding Assay Kit *Green Fluorescence*

20113 25 Tests
EUR 334

Cell Meter™ Live Cell Caspase 8 Binding Assay Kit *Green Fluorescence*

20115 25 Tests
EUR 334

Cell Meter™ Live Cell Caspase 9 Binding Assay Kit *Green Fluorescence*

20117 25 Tests
EUR 334

Cell Meter™ Live Cell Caspase 10 Binding Assay Kit *Green Fluorescence*

20119 25 Tests
EUR 334

Cell Meter™ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence*

20125 25 Tests
EUR 334