Purpose Of Binding Assay

Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader.

Description: Antibiotic Assay Medium No.3 (Assay

Description: Antibiotic Assay Medium No.3 (Assay

Description: Designed for continuous drying operations , general purpose ovens provide temperature homogeneity regulated by microcomputer control system. Stainless steel interiors with easy to clean surface while silicon rubber sealing prevents heat loss and gives stability during operation. - 304 stainless steel, mirror polishing processing, easy to clean and maintain - PID controller with over temperature alarm and Timer function ensures precise and reliable control - Air circulation system with specific air flow channel ensures a good temperature uniformity performance - Silicon door gasket with long lifetime, and easy to change

Description: Designed for continuous drying operations , general purpose ovens provide temperature homogeneity regulated by microcomputer control system. Stainless steel interiors with easy to clean surface while silicon rubber sealing prevents heat loss and gives stability during operation. - Micro-computer intelligent PID control system with LCD display - Forced air convection maintains temperature uniformity - Stainless steel inner chamber and cold rolling steel electrostatic spraying exterior - Easy to clean semicircular corners with adjustable shelves

Description: Designed for continuous drying operations , general purpose ovens provide temperature homogeneity regulated by microcomputer control system. Stainless steel interiors with easy to clean surface while silicon rubber sealing prevents heat loss and gives stability during operation. - Micro-computer intelligent PID control system with LCD display - Forced air convection maintains temperature uniformity - Stainless steel inner chamber and cold rolling steel electrostatic spraying exterior - Easy to clean semicircular corners with adjustable shelves

Description: Designed for continuous drying operations , general purpose ovens provide temperature homogeneity regulated by microcomputer control system. Stainless steel interiors with easy to clean surface while silicon rubber sealing prevents heat loss and gives stability during operation. - Micro-computer intelligent PID control system with LCD display - Forced air convection maintains temperature uniformity - Stainless steel inner chamber and cold rolling steel electrostatic spraying exterior - Easy to clean semicircular corners with adjustable shelves

Description: Designed for continuous drying operations , general purpose ovens provide temperature homogeneity regulated by microcomputer control system. Stainless steel interiors with easy to clean surface while silicon rubber sealing prevents heat loss and gives stability during operation. - Micro-computer intelligent PID control system with LCD display - Forced air convection maintains temperature uniformity - Stainless steel inner chamber and cold rolling steel electrostatic spraying exterior - Easy to clean semicircular corners with adjustable shelves

Description: Designed for continuous drying operations , general purpose ovens provide temperature homogeneity regulated by microcomputer control system. Stainless steel interiors with easy to clean surface while silicon rubber sealing prevents heat loss and gives stability during operation. - Micro-computer intelligent PID control system with LCD display - Forced air convection maintains temperature uniformity - Stainless steel inner chamber and cold rolling steel electrostatic spraying exterior - Easy to clean semicircular corners with adjustable shelves

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LED digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LED digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LED digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LED digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LED digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LCD digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LCD digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LCD digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LCD digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss

Description: Cost effectively designed dual purpose incubator serves both as Incubator and Oven. Two different temperature ranges operated with one single switch provide application versatility. Forced air convection maintains temperature uniformity in the unit. - Micro-computer digital or liquid crystal temperature controller with LCD digital display - Stainless steel interior and cold rolling steel with electrostatic spraying exterior - Door with double glass observation window and adjustable air-tight lock - Silicon rubber sealing prevents heat loss