Aviva Systems Biology Okeh00424 Hmgb1 Elisa Kit (Mouse):96 Wells

KIT ELISA Kit (Mouse) : 96 Wells (OKEH00204)

OKEH00204 96 Wells
EUR 544
Description: Description of target: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.083 ng/mL

Aviva Systems Biology Laboratories manufactures the aviva systems biology okeh00424 hmgb1 elisa kit (mouse):96 wells reagents distributed by Genprice. The Aviva Systems Biology Okeh00424 Hmgb1 Elisa Kit (Mouse):96 Wells reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Aviva Systems Biology. Other Aviva products are available in stock. Specificity: Aviva Category: Systems Group: Biology Okeh00424

IFNG ELISA Kit (Mouse) : 96 Wells (OKEH00078)

96 Wells
EUR 544
Description: Description of target: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.96 pg/mL

IGF2 ELISA Kit (Mouse) : 96 Wells (OKEH00082)

96 Wells
EUR 740
Description: Description of target: This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. It is an imprinted gene that is expressed only from the paternal allele. The encoded protein undergoes proteolytic processing to generate a mature peptide. The transgenic overexpression of this gene in mice results in prenatal overgrowth, polyhydramnios, fetal and neonatal lethality, disproportionate organ overgrowth including tongue enlargement, and skeletal abnormalities. Mice lacking the encoded protein exhibit growth deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 31.27 pg/mL

IL10 ELISA Kit (Mouse) : 96 Wells (OKEH00090)

96 Wells
EUR 544
Description: Description of target: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.8 pg/mL

IL11 ELISA Kit (Mouse) : 96 Wells (OKEH00093)

96 Wells
EUR 635
Description: Description of target: Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.8 pg/mL

IL13 ELISA Kit (Mouse) : 96 Wells (OKEH00100)

96 Wells
EUR 544
Description: Description of target: Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.81 pg/mL

GFAP ELISA Kit (Mouse) : 96 Wells (OKEH00111)

96 Wells
EUR 740
Description: Description of target: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.7 pg/mL

IL2 ELISA Kit (Mouse) : 96 Wells (OKEH00121)

96 Wells
EUR 544
Description: Description of target: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.72 pg/mL

Biology Okeh00424 information

LEP ELISA Kit (Mouse) : 96 Wells (OKEH00151)

OKEH00151 96 Wells
EUR 544
Description: Description of target: May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.165 ng/mL

SELL ELISA Kit (Mouse) : 96 Wells (OKEH00156)

OKEH00156 96 Wells
EUR 544
Description: Description of target: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.089 ng/mL

CCL3 ELISA Kit (Mouse) : 96 Wells (OKEH00163)

OKEH00163 96 Wells
EUR 544
Description: Description of target: Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.88 pg/mL

CCL4 ELISA Kit (Mouse) : 96 Wells (OKEH00166)

OKEH00166 96 Wells
EUR 635
Description: Description of target: Monokine with inflammatory and chemokinetic properties.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.89 pg/mL

MMP13 ELISA Kit (Mouse) : 96 Wells (OKEH00175)

OKEH00175 96 Wells
EUR 688
Description: Description of target: Degrades collagen type I.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL

MMP7 ELISA Kit (Mouse) : 96 Wells (OKEH00183)

OKEH00183 96 Wells
EUR 635
Description: Description of target: May play a role in tissue reorganization.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 41.1 pg/mL

SELP ELISA Kit (Mouse) : 96 Wells (OKEH00198)

OKEH00198 96 Wells
EUR 544
Description: Description of target: Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.081 ng/mL

CCL5 ELISA Kit (Mouse) : 96 Wells (OKEH00199)

OKEH00199 96 Wells
EUR 544
Description: Description of target: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 19.6 pg/mL

TGFA ELISA Kit (Mouse) : 96 Wells (OKEH00207)

OKEH00207 96 Wells
EUR 544
Description: Description of target: TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.81 pg/mL

TGFB1 ELISA Kit (Mouse) : 96 Wells (OKEH00211)

OKEH00211 96 Wells
EUR 544
Description: Description of target: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.8 pg/mL

TIE1 ELISA Kit (Mouse) : 96 Wells (OKEH00213)

OKEH00213 96 Wells
EUR 596
Description: Description of target: Probable protein tyrosine-kinase transmembrane receptor.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.085 ng/mL

TNF ELISA Kit (Mouse) : 96 Wells (OKEH00226)

OKEH00226 96 Wells
EUR 361
Description: Description of target: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 4.15 pg/mL

VEGFA ELISA Kit (Mouse) : 96 Wells (OKEH00236)

OKEH00236 96 Wells
EUR 414
Description: Description of target: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 4.16 pg/mL

VEGFC ELISA Kit (Mouse) : 96 Wells (OKEH00240)

OKEH00240 96 Wells
EUR 557
Description: Description of target: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.9 pg/mL

KDR ELISA Kit (Mouse) : 96 Wells (OKEH00245)

OKEH00245 96 Wells
EUR 662
Description: Description of target: Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.178 ng/mL

AFP ELISA Kit (Mouse) : 96 Wells (OKEH00251)

OKEH00251 96 Wells
EUR 492
Description: Description of target: Binds estrogens, fatty acids and metals.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.18 ng/mL

COL3A1 ELISA Kit (Mouse) : 96 Wells (OKEH00270)

OKEH00270 96 Wells
EUR 662
Description: Description of target: Collagen type III occurs in most soft connective tissues along with type I collagen.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.85 pg/mL