Lc Laboratory Bim

Description: Rabbit polyclonal to Dynein LC 2B.

Description: Rabbit polyclonal to Dynein LC 4.

Description: MAP LC3 beta is a protein encoded by the MAP1LC3B gene which is approximately 14,7 kDa. MAP LC3 beta is localised to the cytoplasm, cytoskeleton and autophagosome membrane. It is involved in pathways such as vesicle-mediated transport, pink/parkin mediated mitophagy, ferroptosis, cellular senescence and the autophagy pathway. MAP LC3 beta is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and plays an important role in neurogenesis. MAP LC3 beta is expressed most abundantly in the heart, brain, skeletal muscle and testis and less expressed in liver. Mutations in the MAP1LC3B gene result in sporadic pheochromocytoma, lacrimal gland adenocarcinoma and spastic paraplegia STJ97398 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous MAP LC3 beta protein.

Description: Rabbit polyclonal to MAP LC3beta.

Description: Bim is a protein encoded by the BCL2L11 gene which is approximately 22,1 kDa. Bim is localised to the mitochondrion. It is involved in the activation of BH3-only proteins, apoptosis modulation and signalling, p75 NTR receptor-mediated signalling and MAPK signalling. It forms a hetero- or homodimers and acts as anti- or pro-apoptotic regulator that is involved in a wide variety of cellular activities. Bim isoform gamma is most abundantly expressed in small intestine and colon. Other isoforms are widely expressed with tissue-specific variation. Mutations in the BCL2L11 gene may result in ocular hyperemia and autoimmune lymphoproliferative syndrome. STJ91225 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous Bim protein which only binds about S59 when S59 is phosphorylated.

Description: BIM Antibody detects endogenous levels of total BIM.

Description: Ki: 20.9 nM for neuromedin B receptorsBombesin (BN) belongs to a family of neuropeptides whose members, as well as their respective receptors, are widely distributed throughout the mammalian central nervous system (CNS).

Description: IC50: 0.02 nM for SSTR3Somatostatin (SRIF) is a cyclic tetradecapeptide that was originally isolated from mammalian hypothalamus and characterized as a physiological regulator of GH secretion from the anterior pituitary.

Description: Bombesin has common effects on the gastrointestinal tract and feeding behavior.

Description: IC50: 10.4 nM for rat pancreas; 2.4 nM for Guinea pig pancreasBombesin has common effects on the gastrointestinal tract and feeding behavior.

Description: IC90: 0.0037 nM for rat SSTR5, 3.6 nM for human SSTR5Somatostatin receptor type 5 is a protein that in humans is encoded by the SSTR5 gene.

Description: Ki: 49 ±14 nM for neuromedin B-induced endpoint in huNMBR cellsNeuromedin B, a mammalian peptide of the bombesinlike peptide family sharing amino acid homology with its amphibian counterpart ranatensin, elicits a diverse array of biological responses in central and peripheral tissues.

Description: BIM antibody detects endogenous levels of total BIM.

Description: Bim Antibody detects endogenous levels of Bim.

Description: Bim Antibody detects endogenous levels of Bim.

Description: Sum Formula: C62H71N11O9S2; CAS# [179188-73-9]

Description: Sum Formula: C62H71N11O9S2; CAS# [179188-73-9]